Personalized risk stratification for the prevention and early detection of breast cancer

Principal Investigator: Bartha Maria Knoppers, Jacques Simard
Theme : Health
Competition : Genomics and Personalized Health
Status : Completed
Start : Apr. 1, 2013
End: Mar. 31, 2017
Budget : $11,382,455.00



Towards an optimal breast cancer screening strategy

Each year, over 22,000 Canadian women are diagnosed with breast cancer, a disease that will claim the lives of 5,000 of them. The routine screening program currently in place is more accessible to women over the age of 50. However, one in five women diagnosed with breast cancer are under the age of 50.


The PERSPECTIVE project (PErsonalised Risk Stratification for Prevention and Early deteCTIon of breast cancer) brings together more than 25 co-researchers, biostatisticians and clinicians from Québec, Ontario, the United States, United Kingdom, the Netherlands and Germany. It aims to develop a decision-making support tool that will help extend the benefits of the current screening program to those women most at risk for breast cancer.


Through involvement with the largest international consortium on the study of breast cancer, the project will help broaden existing knowledge in order to provide better risk stratification tools, fine tune intervention strategies and offer the population more effective tools.

 

To learn more about this project, click here     

 

Co-applicants, End-users and Collaborators:

Irene Andrulis

Ontario Cancer Genetics Network

Antonis Antoniou

Cancer Research UK

Gary Bader

Donnelly Centre for Cellular and Biomolecular Research, University of Toronto

Joanne Castonguay

CIRANO

Anna Chiarelli

Cancer Care Ontario

Jocelyne Chiquette

Université Laval

Nathalie

de Marcellis-Warin

CIRANO

Michel

Dorval

Université Laval

Arnaud

Droit

Université Laval

Douglas

Easton

University of Cambridge, UK

Gareth

Evans

The University of Manchester, UK

William

Foulkes

McGill University

David

Goldgar

University of Utah, USA

Jalila

Jbilou

Moncton University

Yann

Joly

McGill University

Suzanne

Kamel-Reid

University of Toronto

Nora

Pashayan

University College London, UK

Sean

Tavtigian

University of Utah, USA

Michael

Wolfson

University of Ottawa

Éric

Bourbeau

Telus Health - Solutions

Hilary Burton 

Public Health Genomics Foundation, Cambridge, UK

Francine Cléroux

Fondation québécoise du cancer du sein

Gordon Glendon

Ontario Cancer Genetics Network

Bernard Lespérance

Université de Montréal

Linda Rabeneck

Cancer Care Ontario

Marie Rochette

Ministère de la Santé et des Services Sociaux