John Howard White

Affiliation : Université McGill
Organization : Université McGill, Pavillon McIntyre
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About John Howard White

John White obtained his B.Sc. and M.Sc. degrees in Biochemistry and Chemistry at Carleton University in Ottawa. He obtained his PhD from Harvard University studying the molecular mechanisms of bacteriophage replication. Postdoctoral work in the laboratory of Professor Pierre Chambon in Strasbourg, France, introduced him to the molecular mechanisms of action of nuclear receptors, which are activated by ligands such as steroid and thyroid hormones, and the active forms of vitamins A and D. Professor White has been at McGill University since 1991, where he is now a professor in the departments of Physiology and Medicine. In the last 10 years, his laboratory has focused largely on studying the molecular mechanisms of action of vitamin D through the use of high-throughput techniques for identification of genes whose transcription is regulated by the active form of the vitamin. Among other findings, these studies led to the observation that vitamin D directly stimulates antimicrobial innate immunity in humans.

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