Production and engineering of market-ready lysozymes for food animals

Principal Investigator: Adrian Tsang
Theme : Agriculture and Bioproducts
Competition : Genome Canada competition - Genomic Applications Partnership Program (GAPP)
Status : In progress
Start : Oct. 1, 2021
End: Sept. 30, 2024
Budget : $6,100,000.00

The use of antibiotics in food animal production improves growth performance and prevents disease proliferation while at the same time allows antibiotic-resistant bacteria to thrive. Antibiotic-resistant bacteria can be transmitted to humans through the food chain, posing a threat to human health.  Lysozymes are part of the innate immune system of animals and can have equivalent performance to antibiotics. 


This project will use genome-editing technology to produce feed pellet stable lysozyme formulations that will be used to improve gut health and productivity in food animals.  The use of lysozymes in animal feed will improve feed conversion and is expected to save Canadian livestock producers over $300 million in feed costs. It will also reduce antibiotic usage in food animals that could lower the emergence of antibiotic-resistance bacteria and therefore lower the risk of transmission to humans.


Lead Genome Centre: Génome Québec

 User : 

Jeffrey Escobar Elanco Animal Health